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Most Cancer Treatments Are Not Effective Mesothelioma Patients, but Gene Therapy Offers a Hope

Oncologists choose what type of treatment to go with with every patient. The options are endless. There exists no universal treatment option for peritoneal mesothelioma sufferers. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.

The prospects for mesothelioma patients have been grim, but doctors have recently made progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) Each one of these methods have problems. Traditional radiation therapy has not worked well with mesothelioma patients. Researches, concerned about damage to healthy tissue, are looking for ways to aim radiation directly at tumors.

The mesothelial tissue around the tumor is removed by surgery. It is a grueling surgery with unknown benefits to patients. The usual chemotherapy cocktails effective on other cancers are not effective on mesothelioma, and combinations of chemotherapy agents have been tried, but without much success. Like radiation, researchers are focusing their work on controlling the physical location of the treatment with an emphasis on the pleural cavity.

The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. Such treatments include anti-angiogenesis drugs like thalidomide and biologic therapies agent interleukin 2. The new drug pemetrexed (brand name Alimta) has shown good results in extending life with mesotheliomas..

Before acting, oncologists review the stage of mesothelioma, position of the tumor, and age and health status of the patient. Two exotic ways of attacking mesothelioma are gene therapy and photodynamic therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.

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